Collagen.

The same, every batch.

Brought to you by Avenyx Bio, Kobe.

A partnership overview · parth@avenyx.bio · avenyx.bio

Every healing product

stands on collagen.

Days

per batch with full-cycle acid extraction.

Every lot

re-tested by the buyer. Batch-to-batch variability is documented in the literature.

18.6M

diabetic foot ulcers a year. One in three patients dead within five years.

Variability: Aisenbrey & Murphy, Nat Rev Mater 2020 · 18.6M: Armstrong et al., JAMA 2023 · 5-year mortality 30.5%: Armstrong et al., J Foot Ankle Res 2020

Unless.

We keep the helix. Every batch.

Three strands, one helix. We keep it intact.

Stable 47 °C

Helix holds to 47 °C in the CD thermal series.

Reproducible 1 → 10

One batch characterised. Ten-batch study next, one specification.

In hours 32×

Faster than full-cycle acid extraction, which takes days.

Traceable ~35%

Yield from meat and poultry by-products, in-house.

Drag the temperature. Our CD thermal series: the helix holds, then weakens after 47 °C.

25 °C

Research grade first. Medical grade after the manufacturing licence. The M.A.S.S. method is proprietary; no process parameters in this document.

Six institutions did not wait for the licence.

USD 400k of conditional letters of intent

6 institutions. 3 countries. Under 4 months. On samples from our first batches. One condition: the manufacturing licence.

Letters of intent, not revenue. Orders follow the manufacturing licence.

Your collagen bill,
at our price.

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faster extraction than the acid benchmark

Drag to your yearly collagen volume. What it costs at today's benchmark, and at our price.

2 kg a year

Acid benchmark, USD 52.61 a gram

USD 105,220

Avenyx, USD 3.68 a gram, scenario

USD 7,360

Kept in your budget, every year

USD 97,860

Measured	Result, characterised batch
Time per batch	Hours, 32× faster than the full-cycle acid benchmark.
Yield	About 35% in-house, laboratory scale. Ten-batch repeatability study planned, one specification.

Evidence summarised from avenyx.bio/evidence. Price is a scenario, not a quote. Spectra and gel images in conversation.

The helix is there. We measured it.

Circular dichroism Jasco J-1500 · 190 to 260 nm

Positive band near 220 nm. 0.75 mg/mL in 0.5% acetic acid, 0.1 nm pitch, 701 points.

Thermal series 11 spectra · 4 to 54 °C · 222 nm

Holds to 47 °C, then weakens. Hover a row. Not a fitted melting point.

SDS-PAGE 5 lanes · reducing

Same bands as rat-tail and marine. Receptor binding under native conditions; BSA, ovalbumin, myoglobin as controls.

One characterised batch, laboratory scale. Panels are drawn from the instrument metadata; the raw spectra and gel photographs are shown in the meeting.

Source: Avenyx evidence record, instrument metadata 15 May 2026. Yield about 35% in-house.

Three small steps. Nothing at risk.

Talk

Thirty minutes. We listen.

What you make. What collagen costs you in time and tests. You prepare nothing.

Align

We write the specification for you.

You name the tests and the limits. We draft the spec and share our data. The document is yours to keep, whatever you decide.

Join

A conditional letter. No cost. No obligation.

It binds nothing until the licence and can be withdrawn at any time before it. It only keeps your place in the first licensed batches.

Six said yes before the licence. The seventh is easier.

For makers: supply and a co-developed specification. For hospitals and labs: research use and joint evaluation. Letters of intent now; material from the first licensed batches.

Building in Kobe, with Kobe behind us.

CellHaus

Kobe University MIC lab access secured · FBRI and KBIC, the Kobe Biomedical Innovation Cluster · Resident at CellHaus with Mirai Tech City.

Parth Shinde, founder

Built a biotech at university. Built the BITS Goa innovation lab from zero. Selected by Emergent Ventures, SISFS and NSRCEL.

Biology. Prof. Manas Mandal, physiology, Roseman University.

Evidence. Dr. Manish Chaubey, biomedical research, Brown University.

Process. Prof. Devendra Patil, MEMS engineering, BITS Pilani.

Avenyx Bio is the commercial identity of Tvashtr Biotech Pvt. Ltd.

If collagen is in your product, let us talk.

avenyx.bio

xxxxx@xxxxxx.xxx · avenyx.bio · Parth Shinde, Founder

Avenyx Bio · CellHaus, Mirai Tech City, Kobe, Japan · Shared in confidence